Duplication and triplication with staggered breakpoints in human mitochondrial DNA
نویسندگان
چکیده
منابع مشابه
Tandem duplication/triplication correlated with poly-cytosine stretch variation in human mitochondrial DNA D-loop region.
Somatic mutations in the mitochondrial DNA (mtDNA) displacement loop (D-loop) region have been frequently detected in various human cancers. In a previous study, we identified a polyplasmic 260-bp tandem duplication and triplication mutation in the mtDNA D-loop of one gastric cancer. In the present study, we adopted a more sensitive back-to-back polymerase chain reaction method to screen for th...
متن کاملMitoBreak: the mitochondrial DNA breakpoints database
Mitochondrial DNA (mtDNA) rearrangements are key events in the development of many diseases. Investigations of mtDNA regions affected by rearrangements (i.e. breakpoints) can lead to important discoveries about rearrangement mechanisms and can offer important clues about the causes of mitochondrial diseases. Here, we present the mitochondrial DNA breakpoints database (MitoBreak; http://mitobrea...
متن کاملUreteral triplication and contralateral duplication with vesicoureteral reflux.
Ureteral triplication is a rare congenital anomaly of the urinary tract. Since the first description by Warny in 1870, approximately 100 known cases have been reported in the literature, often accompanied by a variety of associated anomalies in contralateral kidney. This report presents a case of ureteral triplication with contralateral duplication and vesicoureteral reflux (VUR) of the upper m...
متن کاملthe past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group
چکیده ندارد.
Ureteral triplication with a contralateral duplication and ureterocele: a case report
We report a 10-year-old boy who presented with nocturnal enuresis. Radiological workup revealed a left ureteral triplication (Smith type 2) with a contralateral duplication and ureterocele. This presentation and its association are extremely rare. The clinical and radiological features are presented here as early diagnosis is important to avoid complications and future renal damage.
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
سال: 1998
ISSN: 0925-4439
DOI: 10.1016/s0925-4439(97)00087-2